BDBM50203126 3,4-dimethoxy-6,7-dihydro-[1,3]dioxolo[4,5-g]pyrido[2,1-a]isoquinolin-5-ylium::9,10-Dimethoxy-5,6-dihydro-[1,3]dioxolo[4,5-g]isoquino[3,2-a]isoquinolin-7-ylium::9,10-Dimethoxy-5,6-dihydro-[1,3]dioxolo[4,5-g]isoquino[3,2-a]isoquinolin-7-ylium chloride::9,10-dimethoxy-5,6-dihydro-[1,3]dioxolo[4,5-g]isoquino[3,2-a]isoquinolin-7-ylium; chloride::BERBERINE::Berberinechloride::CHEMBL12089::berberine dimer::cid_12456

SMILES: COc1ccc2cc3-c4cc5OCOc5cc4CC[n+]3cc2c1OC

InChI Key: InChIKey=YBHILYKTIRIUTE-UHFFFAOYSA-N

Data: 6 KI  67 IC50  3 Kd  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 82 hits for monomerid = 50203126   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tryptophan 2,3-dioxygenase (Human)	BDBM50203126 (Berberinechloride | 9,10-Dimethoxy-5,6-dihydro-[1,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Human)	BDBM50203126 (Berberinechloride | 9,10-Dimethoxy-5,6-dihydro-[1,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Electric eel)	BDBM50203126 (Berberinechloride | 9,10-Dimethoxy-5,6-dihydro-[1,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	374	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carboxylic ester hydrolase (Horse)	BDBM50203126 (Berberinechloride | 9,10-Dimethoxy-5,6-dihydro-[1,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.82E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Electric eel)	BDBM50203126 (Berberinechloride | 9,10-Dimethoxy-5,6-dihydro-[1,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	374	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carboxylic ester hydrolase (Horse)	BDBM50203126 (Berberinechloride | 9,10-Dimethoxy-5,6-dihydro-[1,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.82E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cholinesterase (Horse)	BDBM50203126 (Berberinechloride | 9,10-Dimethoxy-5,6-dihydro-[1,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.82E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Electric eel)	BDBM50203126 (Berberinechloride | 9,10-Dimethoxy-5,6-dihydro-[1,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	374	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Electric eel)	BDBM50203126 (Berberinechloride | 9,10-Dimethoxy-5,6-dihydro-[1,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	374	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cholinesterase (Horse)	BDBM50203126 (Berberinechloride | 9,10-Dimethoxy-5,6-dihydro-[1,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.82E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cholinesterase (Human)	BDBM50203126 (Berberinechloride | 9,10-Dimethoxy-5,6-dihydro-[1,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Human)	BDBM50203126 (Berberinechloride | 9,10-Dimethoxy-5,6-dihydro-[1,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5'-AMP-activated protein kinase catalytic subunit alpha-2 (Human)	BDBM50203126 (Berberinechloride | 9,10-Dimethoxy-5,6-dihydro-[1,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone acetyltransferase p300 (Human)	BDBM50203126 (Berberinechloride | 9,10-Dimethoxy-5,6-dihydro-[1,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.91E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prolyl endopeptidase (Human)	BDBM50203126 (Berberinechloride | 9,10-Dimethoxy-5,6-dihydro-[1,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.42E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Human)	BDBM50203126 (Berberinechloride | 9,10-Dimethoxy-5,6-dihydro-[1,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Human)	BDBM50203126 (Berberinechloride | 9,10-Dimethoxy-5,6-dihydro-[1,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	580	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Human)	BDBM50203126 (Berberinechloride | 9,10-Dimethoxy-5,6-dihydro-[1,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.33E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sentrin-specific protease 8 (Human)	BDBM50203126 (Berberinechloride | 9,10-Dimethoxy-5,6-dihydro-[1,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.66E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sortase family protein (Staphylococcus aureus)	BDBM50203126 (Berberinechloride | 9,10-Dimethoxy-5,6-dihydro-[1,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Electric eel)	BDBM50203126 (Berberinechloride | 9,10-Dimethoxy-5,6-dihydro-[1,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.74E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cell division protein FtsZ (Escherichia coli (strain K12))	BDBM50203126 (Berberinechloride | 9,10-Dimethoxy-5,6-dihydro-[1,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cell division protein FtsZ (Escherichia coli (strain K12))	BDBM50203126 (Berberinechloride | 9,10-Dimethoxy-5,6-dihydro-[1,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cholinesterase (Human)	BDBM50203126 (Berberinechloride | 9,10-Dimethoxy-5,6-dihydro-[1,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.09E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Human)	BDBM50203126 (Berberinechloride | 9,10-Dimethoxy-5,6-dihydro-[1,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuraminidase (Influenza A virus (strain A/USSR/90/1977 H1N1))	BDBM50203126 (Berberinechloride | 9,10-Dimethoxy-5,6-dihydro-[1,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.22E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuraminidase (Influenza A virus (strain A/USSR/90/1977 H1N1))	BDBM50203126 (Berberinechloride | 9,10-Dimethoxy-5,6-dihydro-[1,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.85E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Electric eel)	BDBM50203126 (Berberinechloride | 9,10-Dimethoxy-5,6-dihydro-[1,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	374	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cholinesterase (Horse)	BDBM50203126 (Berberinechloride | 9,10-Dimethoxy-5,6-dihydro-[1,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.82E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50203126 (Berberinechloride | 9,10-Dimethoxy-5,6-dihydro-[1,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.61E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cell division protein FtsZ (Staphylococcus aureus)	BDBM50203126 (Berberinechloride | 9,10-Dimethoxy-5,6-dihydro-[1,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Human)	BDBM50203126 (Berberinechloride | 9,10-Dimethoxy-5,6-dihydro-[1,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	610	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cholinesterase (Horse)	BDBM50203126 (Berberinechloride | 9,10-Dimethoxy-5,6-dihydro-[1,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.82E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Electric eel)	BDBM50203126 (Berberinechloride | 9,10-Dimethoxy-5,6-dihydro-[1,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	374	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prolyl endopeptidase (Human)	BDBM50203126 (Berberinechloride | 9,10-Dimethoxy-5,6-dihydro-[1,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.45E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Human)	BDBM50203126 (Berberinechloride | 9,10-Dimethoxy-5,6-dihydro-[1,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Electric eel)	BDBM50203126 (Berberinechloride | 9,10-Dimethoxy-5,6-dihydro-[1,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	374	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carboxylic ester hydrolase (Horse)	BDBM50203126 (Berberinechloride | 9,10-Dimethoxy-5,6-dihydro-[1,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.82E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Electric eel)	BDBM50203126 (Berberinechloride | 9,10-Dimethoxy-5,6-dihydro-[1,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	374	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cholinesterase (Horse)	BDBM50203126 (Berberinechloride | 9,10-Dimethoxy-5,6-dihydro-[1,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.82E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile salt-activated lipase (Bovine)	BDBM50203126 (Berberinechloride | 9,10-Dimethoxy-5,6-dihydro-[1,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.15E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sortase family protein (Staphylococcus aureus)	BDBM50203126 (Berberinechloride | 9,10-Dimethoxy-5,6-dihydro-[1,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sortase family protein (Staphylococcus aureus)	BDBM50203126 (Berberinechloride | 9,10-Dimethoxy-5,6-dihydro-[1,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prolyl endopeptidase (Human)	BDBM50203126 (Berberinechloride | 9,10-Dimethoxy-5,6-dihydro-[1,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.42E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prolyl endopeptidase (Human)	BDBM50203126 (Berberinechloride | 9,10-Dimethoxy-5,6-dihydro-[1,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.45E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Human)	BDBM50203126 (Berberinechloride | 9,10-Dimethoxy-5,6-dihydro-[1,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cholinesterase (Human)	BDBM50203126 (Berberinechloride | 9,10-Dimethoxy-5,6-dihydro-[1,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.07E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 1B1 (Human)	BDBM50203126 (Berberinechloride | 9,10-Dimethoxy-5,6-dihydro-[1,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	94	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 1B1 (Human)	BDBM50203126 (Berberinechloride | 9,10-Dimethoxy-5,6-dihydro-[1,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sortase family protein (Staphylococcus aureus)	BDBM50203126 (Berberinechloride | 9,10-Dimethoxy-5,6-dihydro-[1,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.21E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair