BDBM50204082 CHEMBL3945820
SMILES CC(c1nc(cn1-c1ccc(cc1F)-c1cc(F)c(CO)c(c1)S(C)(=O)=O)C(C)(C)O)c1c(Cl)cccc1Cl
InChI Key InChIKey=OSCBEESEHIRILI-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50204082
TargetOxysterols receptor LXR-beta/Retinoic acid receptor RXR-alpha(Homo sapiens (Human))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataKi: 13nMAssay Description:Displacement of [3H]-24,25-epoxycholesterol from human LXRbeta/RXRalpha expressed in baculovirus infected Sf9 cells by scintillation proximity analys...More data for this Ligand-Target Pair
TargetOxysterols receptor LXR-alpha/Retinoic acid receptor RXR-alpha(Homo sapiens (Human))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataKi: 17nMAssay Description:Displacement of [3H]-24,25-epoxycholesterol from human LXRalpha/RXRalpha expressed in baculovirus infected Sf9 cells by scintillation proximity analy...More data for this Ligand-Target Pair
Affinity DataEC50: 2nMAssay Description:Agonist activity at LXR-beta in human HeLa cells assessed as induction of ABCA1 by beta-galactosidase/luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 23nMAssay Description:Agonist activity at LXR-beta in human whole blood assessed as ABCA1 gene induction by measuring ABCA1 mRNA level after 4 hrs by SYBR-Green dye-based ...More data for this Ligand-Target Pair
Affinity DataEC50: 25nMAssay Description:Agonist activity at human LXR-beta expressed in African green monkey CV1 cells measured after 18 to 20 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 12nMAssay Description:Agonist activity at human LXR-alpha expressed in African green monkey CV1 cells measured after 18 to 20 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair