BDBM50204579 CHEMBL247866::N-isopropyl-5-phenyl-6-(4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)furo[2,3-d]pyrimidin-4-amine

SMILES: CC(C)Nc1ncnc2oc(c(-c3ccccc3)c12)-c1ccc(OCCN2CCCC2)cc1

InChI Key: InChIKey=SSVDSZIWJBBCNN-UHFFFAOYSA-N

Data: 9 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50204579   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Activated CDC42 kinase 1 (Human)	BDBM50204579 (N-isopropyl-5-phenyl-6-(4-(2-(pyrrolidin-1-yl)etho...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	78	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Angiopoietin-1 receptor (Human)	BDBM50204579 (N-isopropyl-5-phenyl-6-(4-(2-(pyrrolidin-1-yl)etho...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>8.33E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM50204579 (N-isopropyl-5-phenyl-6-(4-(2-(pyrrolidin-1-yl)etho...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	914	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM50204579 (N-isopropyl-5-phenyl-6-(4-(2-(pyrrolidin-1-yl)etho...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.03E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Human)	BDBM50204579 (N-isopropyl-5-phenyl-6-(4-(2-(pyrrolidin-1-yl)etho...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.89E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Human)	BDBM50204579 (N-isopropyl-5-phenyl-6-(4-(2-(pyrrolidin-1-yl)etho...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.43E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Human)	BDBM50204579 (N-isopropyl-5-phenyl-6-(4-(2-(pyrrolidin-1-yl)etho...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ZAP-70 (Human)	BDBM50204579 (N-isopropyl-5-phenyl-6-(4-(2-(pyrrolidin-1-yl)etho...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.27E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Human)	BDBM50204579 (N-isopropyl-5-phenyl-6-(4-(2-(pyrrolidin-1-yl)etho...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	537	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair