BDBM50205477 (Z)-2-((1R,2S)-2-phenylcyclopropylamino)-5-(quinolin-6-ylmethylene)thiazol-4(5H)-one::CHEMBL235345

SMILES: O=C1N=C(N[C@@H]2C[C@H]2c2ccccc2)SC1=Cc1ccc2ncccc2c1

InChI Key: InChIKey=FITGAYHGSUWBQP-UHFFFAOYSA-N

Data: 11 KI  6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 50205477   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 1 (Human)	BDBM50205477 ((Z)-2-((1R,2S)-2-phenylcyclopropylamino)-5-(quinol...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.41E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Human)	BDBM50205477 ((Z)-2-((1R,2S)-2-phenylcyclopropylamino)-5-(quinol...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.58E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Human)	BDBM50205477 ((Z)-2-((1R,2S)-2-phenylcyclopropylamino)-5-(quinol...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.85E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Human)	BDBM50205477 ((Z)-2-((1R,2S)-2-phenylcyclopropylamino)-5-(quinol...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.49E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Human)	BDBM50205477 ((Z)-2-((1R,2S)-2-phenylcyclopropylamino)-5-(quinol...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.34E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Human)	BDBM50205477 ((Z)-2-((1R,2S)-2-phenylcyclopropylamino)-5-(quinol...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.34E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Human)	BDBM50205477 ((Z)-2-((1R,2S)-2-phenylcyclopropylamino)-5-(quinol...) Show SMILES Show InChI	GoogleScholar	UniChem		20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Human)	BDBM50205477 ((Z)-2-((1R,2S)-2-phenylcyclopropylamino)-5-(quinol...) Show SMILES Show InChI	GoogleScholar	UniChem		220	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C delta type (Human)	BDBM50205477 ((Z)-2-((1R,2S)-2-phenylcyclopropylamino)-5-(quinol...) Show SMILES Show InChI	GoogleScholar	UniChem		480	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
RAC-alpha/RAC-beta/RAC-gamma serine/threonine-protein kinase (Human)	BDBM50205477 ((Z)-2-((1R,2S)-2-phenylcyclopropylamino)-5-(quinol...) Show SMILES Show InChI	GoogleScholar	UniChem		>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Human)	BDBM50205477 ((Z)-2-((1R,2S)-2-phenylcyclopropylamino)-5-(quinol...) Show SMILES Show InChI	GoogleScholar	UniChem		>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 (Human)	BDBM50205477 ((Z)-2-((1R,2S)-2-phenylcyclopropylamino)-5-(quinol...) Show SMILES Show InChI	GoogleScholar	UniChem		>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Ephrin type-B receptor 3 (Human)	BDBM50205477 ((Z)-2-((1R,2S)-2-phenylcyclopropylamino)-5-(quinol...) Show SMILES Show InChI	GoogleScholar	UniChem		>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Fyn (Human)	BDBM50205477 ((Z)-2-((1R,2S)-2-phenylcyclopropylamino)-5-(quinol...) Show SMILES Show InChI	GoogleScholar	UniChem		>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2 (Human)	BDBM50205477 ((Z)-2-((1R,2S)-2-phenylcyclopropylamino)-5-(quinol...) Show SMILES Show InChI	GoogleScholar	UniChem		>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3 (Human)	BDBM50205477 ((Z)-2-((1R,2S)-2-phenylcyclopropylamino)-5-(quinol...) Show SMILES Show InChI	GoogleScholar	UniChem		>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4 (Human)	BDBM50205477 ((Z)-2-((1R,2S)-2-phenylcyclopropylamino)-5-(quinol...) Show SMILES Show InChI	GoogleScholar	UniChem		>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair