BDBM50206008 6-hydroxy-7-methoxy-2H-chromen-2-one::CHEMBL390320::isoscopoletin

SMILES: COc1cc2oc(=O)ccc2cc1O

InChI Key: InChIKey=SYTYLPHCLSSCOJ-UHFFFAOYSA-N

Data: 7 KI  7 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50206008   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Induced myeloid leukemia cell differentiation protein Mcl-1 (Human)	BDBM50206008 (6-hydroxy-7-methoxy-2H-chromen-2-one | isoscopolet...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.15E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Xanthine dehydrogenase/oxidase (Human)	BDBM50206008 (6-hydroxy-7-methoxy-2H-chromen-2-one | isoscopolet...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.38E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Polyunsaturated fatty acid 5-lipoxygenase (Human)	BDBM50206008 (6-hydroxy-7-methoxy-2H-chromen-2-one | isoscopolet...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Polyunsaturated fatty acid lipoxygenase ALOX15 (Rabbit)	BDBM50206008 (6-hydroxy-7-methoxy-2H-chromen-2-one | isoscopolet...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.51E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Prostaglandin G/H synthase 2 (Human)	BDBM50206008 (6-hydroxy-7-methoxy-2H-chromen-2-one | isoscopolet...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Aldo-keto reductase family 1 member B1 (Human)	BDBM50206008 (6-hydroxy-7-methoxy-2H-chromen-2-one | isoscopolet...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.62E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Sorbitol dehydrogenase (Human)	BDBM50206008 (6-hydroxy-7-methoxy-2H-chromen-2-one | isoscopolet...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 12 (Human)	BDBM50206008 (6-hydroxy-7-methoxy-2H-chromen-2-one | isoscopolet...) Show SMILES Show InChI	GoogleScholar	UniChem		4.14E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 13 (Human)	BDBM50206008 (6-hydroxy-7-methoxy-2H-chromen-2-one | isoscopolet...) Show SMILES Show InChI	GoogleScholar	UniChem		5.27E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 9 (Human)	BDBM50206008 (6-hydroxy-7-methoxy-2H-chromen-2-one | isoscopolet...) Show SMILES Show InChI	GoogleScholar	UniChem		7.37E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 1 (Human)	BDBM50206008 (6-hydroxy-7-methoxy-2H-chromen-2-one | isoscopolet...) Show SMILES Show InChI	GoogleScholar	UniChem		1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Induced myeloid leukemia cell differentiation protein Mcl-1 (Human)	BDBM50206008 (6-hydroxy-7-methoxy-2H-chromen-2-one | isoscopolet...) Show SMILES Show InChI	GoogleScholar	UniChem		1.59E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 7 (Human)	BDBM50206008 (6-hydroxy-7-methoxy-2H-chromen-2-one | isoscopolet...) Show SMILES Show InChI	GoogleScholar	UniChem		2.38E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 2 (Human)	BDBM50206008 (6-hydroxy-7-methoxy-2H-chromen-2-one | isoscopolet...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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