BDBM50206269 4-(4-(2-aminopropan-2-yl)phenyl)-N-(3-bromophenyl)-5-chloropyrimidin-2-amine::CHEMBL234443

SMILES CC(C)(N)c1ccc(cc1)-c1nc(Nc2cccc(Br)c2)ncc1Cl

InChI Key InChIKey=HXPISZQYKPVCLW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50206269   

TargetVascular endothelial growth factor receptor 2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206269(4-(4-(2-aminopropan-2-yl)phenyl)-N-(3-bromophenyl)...)
Affinity DataIC50: 348nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206269(4-(4-(2-aminopropan-2-yl)phenyl)-N-(3-bromophenyl)...)
Affinity DataIC50: 1.04E+3nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed