BDBM50206506 9-beta-D-arabinofuranosylguanosine::CHEMBL240933

SMILES c1nc2c(n1[C@H]3[C@H]([C@@H]([C@H](O3)COP(=O)(O)O)O)O)N=C(NC2=O)N

InChI Key InChIKey=RQFCJASXJCIDSX-UHFFFAOYSA-N

Data  6 IC50

PDB links: 4 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50206506   

TargetDiacylglycerol kinase 1(Fruit fly)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50206506(9-beta-D-arabinofuranosylguanosine | CHEMBL240933)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of Drosophila melanogaster dGK assessed as [methyl-3H]dThd phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetThymidine kinase(HHV-1)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50206506(9-beta-D-arabinofuranosylguanosine | CHEMBL240933)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of HSV1 TK assessed as [methyl-3H]dThd phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetThymidine kinase, cytosolic(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50206506(9-beta-D-arabinofuranosylguanosine | CHEMBL240933)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of human TK1 assessed as [methyl-3H]dThd phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetThymidine kinase 2, mitochondrial(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50206506(9-beta-D-arabinofuranosylguanosine | CHEMBL240933)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of human TK2 assessed as [methyl-3H]dThd phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetDeoxynucleoside kinase(Fruit fly)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50206506(9-beta-D-arabinofuranosylguanosine | CHEMBL240933)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of Drosophila melanogaster dNK assessed as [methyl-3H]dThd phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetThymidine kinase(HHV-3)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50206506(9-beta-D-arabinofuranosylguanosine | CHEMBL240933)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of VZV TK assessed as [methyl-3H]dThd phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed