BDBM50207302 CHEMBL3962191

SMILES COc1cc(ccc1O)-c1cc2ccccc2c(=O)o1

InChI Key InChIKey=MFZUHLDMZUBWPB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50207302   

TargetProstaglandin E synthase(Human)
Bhupat and Jyoti Mehta School of Biosciences

Curated by ChEMBL
LigandPNGBDBM50207302(CHEMBL3962191)
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of mPGES1 in human HeLa cells assessed as reduction in TNF-alpha induced PGE2 production preincubated for 2 hrs followed by TNF-alpha addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Bhupat and Jyoti Mehta School of Biosciences

Curated by ChEMBL
LigandPNGBDBM50207302(CHEMBL3962191)
Affinity DataIC50: 2.28E+4nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21 assessed as decrease in 5-HPETE production preincubated with enzyme followed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details Article
PubMed