BDBM50208345 4-((2-methylquinolin-4-yl)methoxy)-N-((5-oxo-4,5-dihydro-1H-1,2,4-triazol-3-yl)methyl)benzamide::CHEMBL228267

SMILES Cc1cc(COc2ccc(cc2)C(=O)NCc2n[nH]c(=O)[nH]2)c2ccccc2n1

InChI Key InChIKey=HGNMRIKSORWTLJ-UHFFFAOYSA-N

Data  4 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50208345   

TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50208345(4-((2-methylquinolin-4-yl)methoxy)-N-((5-oxo-4,5-d...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of pTACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50208345(4-((2-methylquinolin-4-yl)methoxy)-N-((5-oxo-4,5-d...)
Affinity DataKi: >2.13E+3nMAssay Description:Binding affinity to MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50208345(4-((2-methylquinolin-4-yl)methoxy)-N-((5-oxo-4,5-d...)
Affinity DataKi: >3.33E+3nMAssay Description:Binding affinity to MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50208345(4-((2-methylquinolin-4-yl)methoxy)-N-((5-oxo-4,5-d...)
Affinity DataKi: >4.95E+3nMAssay Description:Binding affinity to MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50208345(4-((2-methylquinolin-4-yl)methoxy)-N-((5-oxo-4,5-d...)
Affinity DataKi: >5.03E+3nMAssay Description:Binding affinity to MMP12More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed