BDBM50208826 (+)-Pinoresinol::4-[(1S,3aR,4S,6aR)-4-(4-hydroxy-3-methoxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-2-methoxyphenol::CHEMBL267963

SMILES COc1cc(ccc1O)[C@H]2[C@@H]3CO[C@H]([C@@H]3CO2)c4ccc(c(c4)OC)O

InChI Key InChIKey=HGXBRUKMWQGOIE-UHFFFAOYSA-N

Data  2 KI  1 IC50

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50208826   

TargetLysosomal alpha-glucosidase(Rat)
Chulalongkorn University

Curated by ChEMBL
LigandPNGBDBM50208826(4-[(1S,3aR,4S,6aR)-4-(4-hydroxy-3-methoxyphenyl)te...)
Affinity DataIC50: 3.43E+4nMAssay Description:Inhibition of rat intestinal maltase using maltose as substrate preincubated for 10 mins before substrate addition by glucose oxidase methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Rat)
Chulalongkorn University

Curated by ChEMBL
LigandPNGBDBM50208826(4-[(1S,3aR,4S,6aR)-4-(4-hydroxy-3-methoxyphenyl)te...)
Affinity DataKi:  2.88E+5nMAssay Description:Competitive inhibition of rat intestinal maltase using maltose as substrate assessed as dissociation of enzyme-inhibitor complex at 0.1 to 1 mg/ml by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Rat)
Chulalongkorn University

Curated by ChEMBL
LigandPNGBDBM50208826(4-[(1S,3aR,4S,6aR)-4-(4-hydroxy-3-methoxyphenyl)te...)
Affinity DataKi:  1.34E+6nMAssay Description:Non-competitive inhibition of rat intestinal maltase using maltose as substrate assessed as dissociation of enzyme-substrate-inhibitor complex at 0.1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed