BDBM50209938 (2S,3S,11bS)-3-butyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1-a]isoquinolin-2-amine::CHEMBL234412

SMILES CCCC[C@H]1CN2CCc3cc(OC)c(OC)cc3[C@@H]2C[C@@H]1N

InChI Key InChIKey=IYTDSNSLAQHLJL-XIRDDKMYSA-N

Data  5 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50209938   

TargetCytochrome P450 3A4(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50209938((2S,3S,11bS)-3-butyl-9,10-dimethoxy-2,3,4,6,7,11b-...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50209938((2S,3S,11bS)-3-butyl-9,10-dimethoxy-2,3,4,6,7,11b-...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50209938((2S,3S,11bS)-3-butyl-9,10-dimethoxy-2,3,4,6,7,11b-...)
Affinity DataIC50:  710nMAssay Description:Inhibition of human DPP4 expressed in baculovirus systemMore data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50209938((2S,3S,11bS)-3-butyl-9,10-dimethoxy-2,3,4,6,7,11b-...)
Affinity DataIC50:  520nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
TargetCytochrome P450 2D6(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50209938((2S,3S,11bS)-3-butyl-9,10-dimethoxy-2,3,4,6,7,11b-...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed