BDBM50210399 4-phenyl-1-(phenyl(thiophen-2-yl)methyl)piperidin-4-ol::CHEMBL228740

SMILES OC1(CCN(CC1)C(c1cccs1)c1ccccc1)c1ccccc1

InChI Key InChIKey=AEUSAZUUXLNHOA-UHFFFAOYSA-N

Data  4 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50210399   

TargetNociceptin receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50210399(4-phenyl-1-(phenyl(thiophen-2-yl)methyl)piperidin-...)
Show SMILES OC1(CCN(CC1)C(c1cccs1)c1ccccc1)c1ccccc1
Show InChI InChI=1S/C22H23NOS/c24-22(19-10-5-2-6-11-19)13-15-23(16-14-22)21(20-12-7-17-25-20)18-8-3-1-4-9-18/h1-12,17,21,24H,13-16H2
Affinity DataKi:  35nMAssay Description:Agonist activity at human NOP receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50210399(4-phenyl-1-(phenyl(thiophen-2-yl)methyl)piperidin-...)
Show SMILES OC1(CCN(CC1)C(c1cccs1)c1ccccc1)c1ccccc1
Show InChI InChI=1S/C22H23NOS/c24-22(19-10-5-2-6-11-19)13-15-23(16-14-22)21(20-12-7-17-25-20)18-8-3-1-4-9-18/h1-12,17,21,24H,13-16H2
Affinity DataKi:  405nMAssay Description:Displacement of [3H]diprenorphine from human MOP receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50210399(4-phenyl-1-(phenyl(thiophen-2-yl)methyl)piperidin-...)
Show SMILES OC1(CCN(CC1)C(c1cccs1)c1ccccc1)c1ccccc1
Show InChI InChI=1S/C22H23NOS/c24-22(19-10-5-2-6-11-19)13-15-23(16-14-22)21(20-12-7-17-25-20)18-8-3-1-4-9-18/h1-12,17,21,24H,13-16H2
Affinity DataKi:  971nMAssay Description:Displacement of [3H]diprenorphine from human KOP receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50210399(4-phenyl-1-(phenyl(thiophen-2-yl)methyl)piperidin-...)
Show SMILES OC1(CCN(CC1)C(c1cccs1)c1ccccc1)c1ccccc1
Show InChI InChI=1S/C22H23NOS/c24-22(19-10-5-2-6-11-19)13-15-23(16-14-22)21(20-12-7-17-25-20)18-8-3-1-4-9-18/h1-12,17,21,24H,13-16H2
Affinity DataKi:  7.85E+3nMAssay Description:Displacement of [3H]diprenorphine from human DOP receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair