BDBM50214034 (1S,3S)-N1-(7-methoxy-4-methylquinolin-2-yl)-N3-(thiophen-3-ylmethyl)cyclohexane-1,3-diamine::CHEMBL250516
SMILES COc1ccc2c(C)cc(N[C@H]3CCC[C@@H](C3)NCc3ccsc3)nc2c1
InChI Key InChIKey=QUSHDRQZFJGEQA-ROUUACIJSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50214034
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Antagonist activity at human MCHR1 expressed in HEK293 cells assessed as [35S]GTPgammaS accumulationMore data for this Ligand-Target Pair