BDBM50214928 (Z)-(2-((9-hydroxy-10-methoxy-2,2,4-trimethyl-1,2-dihydro-4aH-chromeno[3,4-f]quinolin-5(12aH)-ylidene)methyl)thiophen-3-yl)(piperidin-1-yl)methanone::CHEMBL232573
SMILES COc1c(O)ccc2O\C(=C/c3sccc3C(=O)N3CCCCC3)C3=C(C=CC4NC(C)(C)C=C(C)C34)c12
InChI Key InChIKey=YNLLLFCGVZQNDE-JLPGSUDCSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50214928
Affinity DataKi: 1.40nMAssay Description:Displacement of radiolabeled dexamethasone from glucocorticoid receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 0.200nMAssay Description:Agonist activity at GR by GRE activation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.10nMAssay Description:Antagonist activity at GR assessed as inhibition of dexamethasone-induced GRE activationMore data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Activity at GR assessed as repression of TNFalpha and IL 1beta induced E-selectin responseMore data for this Ligand-Target Pair