BDBM50216502 4-(3-hydroxy-phenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid ethyl ester::CHEMBL236789::monastrol::rac-monastrol

SMILES: CCOC(=O)C1C(NC(=S)N=C1C)c1cccc(O)c1

InChI Key: InChIKey=PSKVISJISBFCKP-UHFFFAOYSA-N

Data: 11 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50216502   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kinesin-like protein KIF11 (Human)	BDBM50216502 (monastrol | rac-monastrol | 4-(3-hydroxy-phenyl)-6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Kinesin-like protein KIF11 (Human)	BDBM50216502 (monastrol | rac-monastrol | 4-(3-hydroxy-phenyl)-6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Human)	BDBM50216502 (monastrol | rac-monastrol | 4-(3-hydroxy-phenyl)-6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Human)	BDBM50216502 (monastrol | rac-monastrol | 4-(3-hydroxy-phenyl)-6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.23E+4	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Human)	BDBM50216502 (monastrol | rac-monastrol | 4-(3-hydroxy-phenyl)-6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.47E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Aurora kinase A (Human)	BDBM50216502 (monastrol | rac-monastrol | 4-(3-hydroxy-phenyl)-6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Human)	BDBM50216502 (monastrol | rac-monastrol | 4-(3-hydroxy-phenyl)-6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Human)	BDBM50216502 (monastrol | rac-monastrol | 4-(3-hydroxy-phenyl)-6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.45E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Human)	BDBM50216502 (monastrol | rac-monastrol | 4-(3-hydroxy-phenyl)-6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Human)	BDBM50216502 (monastrol | rac-monastrol | 4-(3-hydroxy-phenyl)-6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Kinesin-like protein KIFC1 (Human)	BDBM50216502 (monastrol | rac-monastrol | 4-(3-hydroxy-phenyl)-6...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair