BDBM50218290 5-chloro-N-((1R,2S,4S)-4-(hydroxymethyl)-2-(4-(2-oxopyridin-1(2H)-yl)benzamido)cyclopentyl)thiophene-2-carboxamide::CHEMBL237065
SMILES OC[C@@H]1C[C@@H](NC(=O)c2ccc(Cl)s2)[C@H](C1)NC(=O)c1ccc(cc1)-n1ccccc1=O
InChI Key InChIKey=LWARIAPUYJUPKK-JCGIZDLHSA-N
Data 7 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50218290
Affinity DataKi: 0.560nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
Affinity DataKi: >1.08E+4nMAssay Description:Inhibition of human plasma kallikreinMore data for this Ligand-Target Pair
Affinity DataKi: >1.10E+4nMAssay Description:Inhibition of human factor 7aMore data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataKi: >1.40E+4nMAssay Description:Inhibition of human urokinaseMore data for this Ligand-Target Pair
Affinity DataKi: >2.10E+4nMAssay Description:Inhibition of human activated protein CMore data for this Ligand-Target Pair
Affinity DataKi: >2.10E+4nMAssay Description:Inhibition of human tissue plasminogen activatorMore data for this Ligand-Target Pair
Affinity DataKi: >2.20E+4nMAssay Description:Inhibition of human PlasminMore data for this Ligand-Target Pair