BDBM50218734 8-chloro-5,10-dihydro-dibenzo[b,e][1,4]diazepin-11-one::8-chloro-5H-dibenzo[b,e][1,4]diazepin-11(10H)-one::CHEMBL396034::Chk1_8

SMILES: c1ccc2c(c1)C(=O)Nc3cc(ccc3N2)Cl

InChI Key: InChIKey=YVWNDABPZGGQFE-UHFFFAOYSA-N

Data: 2 KI  3 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50218734   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase Chk1 (Human)	BDBM50218734 (CHEMBL396034 | Chk1_8 | 8-chloro-5H-dibenzo[b,e][1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk1 (Human)	BDBM50218734 (CHEMBL396034 | Chk1_8 | 8-chloro-5H-dibenzo[b,e][1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.72E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk1 (Human)	BDBM50218734 (CHEMBL396034 | Chk1_8 | 8-chloro-5H-dibenzo[b,e][1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk1 (Human)	BDBM50218734 (CHEMBL396034 | Chk1_8 | 8-chloro-5H-dibenzo[b,e][1...) Show SMILES Show InChI	GoogleScholar	UniChem		1.58E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk1 [2-280] (Human)	BDBM50218734 (CHEMBL396034 | Chk1_8 | 8-chloro-5H-dibenzo[b,e][1...) Show SMILES Show InChI	GoogleScholar	UniChem		1.72E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair