BDBM50220278 1-((2R,6S)-1-(4-chlorophenylsulfonyl)-6-(2,2,2-trifluoroethyl)piperidin-2-yl)cyclopropyl 4-(2-hydroxyethyl)piperazine-1-carboxylate::CHEMBL240071
SMILES OCCN1CCN(CC1)C(=O)OC1(CC1)[C@H]1CCC[C@@H](CC(F)(F)F)N1S(=O)(=O)c1ccc(Cl)cc1
InChI Key InChIKey=OEMOPPHKWFSUEF-AZUAARDMSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 50220278
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of gamma-secretase assessed as reduction of membrane Abeta40 levelMore data for this Ligand-Target Pair