BDBM50221970 (2S,3S)-2-((1r,4S)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)cyclohexyl)-3-amino-4-(3,3-difluoropyrrolidin-1-yl)-N,N-dimethyl-4-oxobutanamide::(2S,3S)-3-AMINO-4-(3,3-DIFLUOROPYRROLIDIN-1-YL)-N,N-DIMETHYL-4-OXO-2-(TRANS-4-[1,2,4]TRIAZOLO[1,5-A]PYRIDIN-6-YLCYCLOHEXYL)BUTANAMIDE::CHEMBL437557

SMILES CN(C)C(=O)[C@H]([C@H](N)C(=O)N1CCC(F)(F)C1)[C@H]1CC[C@@H](CC1)c1ccc2ncnn2c1

InChI Key InChIKey=JNAZOMVWUGPITI-LNMJFAINSA-N

Data  5 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50221970   

TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50221970((2S,3S)-2-((1r,4S)-4-([1,2,4]triazolo[1,5-a]pyridi...)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of human DPP8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 9(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50221970((2S,3S)-2-((1r,4S)-4-([1,2,4]triazolo[1,5-a]pyridi...)
Affinity DataIC50:  3.80E+4nMAssay Description:Inhibition of human DPP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50221970((2S,3S)-2-((1r,4S)-4-([1,2,4]triazolo[1,5-a]pyridi...)
Affinity DataIC50:  130nMAssay Description:Inhibition of human DPP4 in presence of 50 % human serumMore data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50221970((2S,3S)-2-((1r,4S)-4-([1,2,4]triazolo[1,5-a]pyridi...)
Affinity DataIC50:  4.80nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50221970((2S,3S)-2-((1r,4S)-4-([1,2,4]triazolo[1,5-a]pyridi...)
Affinity DataIC50: >9.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed