BDBM50222303 4',6,7,-trihydroxyisoflavone::4',6,7-trihydroxyisoflavone::6,7,3'-trihydroxyisoflavone::6,7,4'-trihydroxyisoflavone::6,7-dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one::CHEMBL239156::IR-1

SMILES: c1cc(ccc1C2=COc3cc(c(cc3C2=O)O)O)O

InChI Key: InChIKey=GYLUFQJZYAJQDI-UHFFFAOYSA-N

Data: 9 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50222303   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Polyunsaturated fatty acid lipoxygenase ALOX15B (Human)	BDBM50222303 (6,7,4'-trihydroxyisoflavone | 4',6,7,-trihydroxyis...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	7.3	25
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Polyunsaturated fatty acid 5-lipoxygenase (Human)	BDBM50222303 (6,7,4'-trihydroxyisoflavone | 4',6,7,-trihydroxyis...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	7.3	25
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DNA topoisomerase 2-alpha (Human)	BDBM50222303 (6,7,4'-trihydroxyisoflavone | 4',6,7,-trihydroxyis...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.62E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Polyunsaturated fatty acid lipoxygenase ALOX15B (Human)	BDBM50222303 (6,7,4'-trihydroxyisoflavone | 4',6,7,-trihydroxyis...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Polyunsaturated fatty acid lipoxygenase ALOX15 (Human)	BDBM50222303 (6,7,4'-trihydroxyisoflavone | 4',6,7,-trihydroxyis...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Polyunsaturated fatty acid lipoxygenase ALOX12 (Human)	BDBM50222303 (6,7,4'-trihydroxyisoflavone | 4',6,7,-trihydroxyis...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Xanthine dehydrogenase/oxidase (Human)	BDBM50222303 (6,7,4'-trihydroxyisoflavone | 4',6,7,-trihydroxyis...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
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Xanthine dehydrogenase/oxidase (Human)	BDBM50222303 (6,7,4'-trihydroxyisoflavone | 4',6,7,-trihydroxyis...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosinase (Mouse)	BDBM50222303 (6,7,4'-trihydroxyisoflavone | 4',6,7,-trihydroxyis...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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