BDBM50223588 CHEMBL330372::DNDI1417460

SMILES C(Oc1ccc(cc1)-c1cc([nH]n1)C1CCNCC1)c1ccccc1

InChI Key InChIKey=DZMLWDRXHPVPGK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50223588   

TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50223588(DNDI1417460 | CHEMBL330372)
Affinity DataIC50: 3.83E+5nMAssay Description:Iinhibitory activity against Escherichia coli DNA gyraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50223588(DNDI1417460 | CHEMBL330372)
Affinity DataIC50: 3.83E+5nMAssay Description:Inhibitory activity against Escherichia coli DNA gyraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2018
Entry Details Article
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50223588(DNDI1417460 | CHEMBL330372)
Affinity DataIC50: 3.83E+5nMAssay Description:Inhibition of Escherichia coli DNA gyrase using positively supercoiled pBR322 DNA as substrate incubated for 1 hr by based agarose gel electrophoresi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha/2-beta(Human)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50223588(DNDI1417460 | CHEMBL330372)
Affinity DataIC50: 5.99E+5nMAssay Description:Inhibitory activity against human DNA topoisomerase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2018
Entry Details Article
PubMed