BDBM50224734 2-(4-(6-Chloro-2-(4-(dimethylamino)phenyl)-3H-imidazo[4,5-b]-pyridin-7-yl)piperazin-1-yl)-N-(thiazol-2-yl)acetamide::2-(4-(6-chloro-2-(4-(dimethylamino)phenyl)-3H-imidazo[4,5-b]pyridin-7-yl)piperazin-1-yl)-N-(thiazol-2-yl)acetamide::CHEMBL392525

SMILES: CN(C)c1ccc(cc1)-c1nc2ncc(Cl)c(N3CCN(CC(=O)Nc4nccs4)CC3)c2[nH]1

InChI Key: InChIKey=QYKHWEFPFAGNEV-UHFFFAOYSA-N

Data: 11 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50224734   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 2A6 (Human)	BDBM50224734 (2-(4-(6-chloro-2-(4-(dimethylamino)phenyl)-3H-imid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Aurora kinase B (Human)	BDBM50224734 (2-(4-(6-chloro-2-(4-(dimethylamino)phenyl)-3H-imid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	198	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2D6 (Human)	BDBM50224734 (2-(4-(6-chloro-2-(4-(dimethylamino)phenyl)-3H-imid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Aurora kinase C (Human)	BDBM50224734 (2-(4-(6-chloro-2-(4-(dimethylamino)phenyl)-3H-imid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	227	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM50224734 (2-(4-(6-chloro-2-(4-(dimethylamino)phenyl)-3H-imid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 1A2 (Human)	BDBM50224734 (2-(4-(6-chloro-2-(4-(dimethylamino)phenyl)-3H-imid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C19 (Human)	BDBM50224734 (2-(4-(6-chloro-2-(4-(dimethylamino)phenyl)-3H-imid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Aurora kinase A (Human)	BDBM50224734 (2-(4-(6-chloro-2-(4-(dimethylamino)phenyl)-3H-imid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C9 (Human)	BDBM50224734 (2-(4-(6-chloro-2-(4-(dimethylamino)phenyl)-3H-imid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Aurora kinase A (Human)	BDBM50224734 (2-(4-(6-chloro-2-(4-(dimethylamino)phenyl)-3H-imid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
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Aurora kinase A (Human)	BDBM50224734 (2-(4-(6-chloro-2-(4-(dimethylamino)phenyl)-3H-imid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
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