BDBM50227997 (6S,7S)-6-[4-(3-isopropyl-phenyl)-piperidine-1-carbonyl]-5-aza-spiro[2.5]octane-7-carboxylic acid hydroxyamide::CHEMBL253460
SMILES CC(C)c1cccc(c1)C1CCN(CC1)C(=O)[C@H]1NCC2(CC2)C[C@@H]1C(=O)NO
InChI Key InChIKey=GNZQSAUOKCWSHO-PMACEKPBSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50227997
TargetDisintegrin and metalloproteinase domain-containing protein 10(Homo sapiens (Human))
Incyte
Curated by ChEMBL
Incyte
Curated by ChEMBL
Affinity DataIC50: 139nMAssay Description:Inhibition of HER2 sheddase in BT474 cells by extracellular domain shedding assayMore data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+3nMAssay Description:Binding affinity to MMP3More data for this Ligand-Target Pair
Affinity DataIC50: 1.39E+3nMAssay Description:Binding affinity to MMP2More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 10(Homo sapiens (Human))
Incyte
Curated by ChEMBL
Incyte
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of HER2 sheddase in BT474 cells by extracellular domain shedding assayMore data for this Ligand-Target Pair