BDBM50228080 2',15'-dimethyl-5,5'-dioxo-(9'R)-spiro[tetrahydrofuran-2,14'-tetracyclo[8.7.0.02,7.011,15]heptadec-6'-ene]-9-yl ethanethioate::2',15'-dimethyl-5,5'-dioxospiro[tetrahydrofuran-2,14'-tetracyclo[8.7.0.02,7.011,15]heptadec-6'-ene]-9-yl ethanethioate::2',15'-dimethyl-5,5'-dioxospiro[tetrahydrofuran-2,14'-tetracyclo[8.7.0.02,7.011,15]heptadec-6'-ene]-9-yl ethanethioate(Spiranolactone)::Aldactone::CHEMBL1393::S-(2'R,7R,8R,9S,10R,13S,14S)-10,13-dimethyl-3,5'-dioxo-1,2,3,4',5',6,7,8,9,10,11,12,13,14,15,16-hexadecahydro-3'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-7-yl ethanethioate::SPIRONOLACTONE::Spiranolactone::cid_5833

SMILES: CC(=O)S[C@@H]1CC2=CC(=O)CC[C@]2(C)[C@H]2CC[C@@]3(C)[C@@H](CC[C@@]33CCC(=O)O3)[C@H]12

InChI Key: InChIKey=LXMSZDCAJNLERA-UHFFFAOYSA-N

Data: 6 KI  34 IC50  4 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 44 hits for monomerid = 50228080   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mineralocorticoid receptor (Human)	BDBM50228080 (Spiranolactone | S-(2'R,7R,8R,9S,10R,13S,14S)-10,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Human)	BDBM50228080 (Spiranolactone | S-(2'R,7R,8R,9S,10R,13S,14S)-10,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.92E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Progesterone receptor (Human)	BDBM50228080 (Spiranolactone | S-(2'R,7R,8R,9S,10R,13S,14S)-10,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor (Human)	BDBM50228080 (Spiranolactone | S-(2'R,7R,8R,9S,10R,13S,14S)-10,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Rat)	BDBM50228080 (Spiranolactone | S-(2'R,7R,8R,9S,10R,13S,14S)-10,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	676	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
ATP-dependent translocase ABCB1 (Human)	BDBM50228080 (Spiranolactone | S-(2'R,7R,8R,9S,10R,13S,14S)-10,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.36E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Multidrug and toxin extrusion protein 1 (Human)	BDBM50228080 (Spiranolactone | S-(2'R,7R,8R,9S,10R,13S,14S)-10,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.86E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM50228080 (Spiranolactone | S-(2'R,7R,8R,9S,10R,13S,14S)-10,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	670	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM50228080 (Spiranolactone | S-(2'R,7R,8R,9S,10R,13S,14S)-10,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Human)	BDBM50228080 (Spiranolactone | S-(2'R,7R,8R,9S,10R,13S,14S)-10,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Human)	BDBM50228080 (Spiranolactone | S-(2'R,7R,8R,9S,10R,13S,14S)-10,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM50228080 (Spiranolactone | S-(2'R,7R,8R,9S,10R,13S,14S)-10,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	523	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Progesterone receptor (Human)	BDBM50228080 (Spiranolactone | S-(2'R,7R,8R,9S,10R,13S,14S)-10,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Progesterone receptor (Human)	BDBM50228080 (Spiranolactone | S-(2'R,7R,8R,9S,10R,13S,14S)-10,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Human)	BDBM50228080 (Spiranolactone | S-(2'R,7R,8R,9S,10R,13S,14S)-10,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Progesterone receptor (Human)	BDBM50228080 (Spiranolactone | S-(2'R,7R,8R,9S,10R,13S,14S)-10,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Human)	BDBM50228080 (Spiranolactone | S-(2'R,7R,8R,9S,10R,13S,14S)-10,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Human)	BDBM50228080 (Spiranolactone | S-(2'R,7R,8R,9S,10R,13S,14S)-10,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM50228080 (Spiranolactone | S-(2'R,7R,8R,9S,10R,13S,14S)-10,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Progesterone receptor (Human)	BDBM50228080 (Spiranolactone | S-(2'R,7R,8R,9S,10R,13S,14S)-10,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	650	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM50228080 (Spiranolactone | S-(2'R,7R,8R,9S,10R,13S,14S)-10,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	670	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor beta (Human)	BDBM50228080 (Spiranolactone | S-(2'R,7R,8R,9S,10R,13S,14S)-10,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cystic fibrosis transmembrane conductance regulator (Human)	BDBM50228080 (Spiranolactone | S-(2'R,7R,8R,9S,10R,13S,14S)-10,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor beta (Human)	BDBM50228080 (Spiranolactone | S-(2'R,7R,8R,9S,10R,13S,14S)-10,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Human)	BDBM50228080 (Spiranolactone | S-(2'R,7R,8R,9S,10R,13S,14S)-10,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM50228080 (Spiranolactone | S-(2'R,7R,8R,9S,10R,13S,14S)-10,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Human)	BDBM50228080 (Spiranolactone | S-(2'R,7R,8R,9S,10R,13S,14S)-10,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.05E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Human)	BDBM50228080 (Spiranolactone | S-(2'R,7R,8R,9S,10R,13S,14S)-10,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Human)	BDBM50228080 (Spiranolactone | S-(2'R,7R,8R,9S,10R,13S,14S)-10,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	76	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Human)	BDBM50228080 (Spiranolactone | S-(2'R,7R,8R,9S,10R,13S,14S)-10,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Human)	BDBM50228080 (Spiranolactone | S-(2'R,7R,8R,9S,10R,13S,14S)-10,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Progesterone receptor (Human)	BDBM50228080 (Spiranolactone | S-(2'R,7R,8R,9S,10R,13S,14S)-10,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	650	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Human)	BDBM50228080 (Spiranolactone | S-(2'R,7R,8R,9S,10R,13S,14S)-10,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM50228080 (Spiranolactone | S-(2'R,7R,8R,9S,10R,13S,14S)-10,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Human)	BDBM50228080 (Spiranolactone | S-(2'R,7R,8R,9S,10R,13S,14S)-10,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Human)	BDBM50228080 (Spiranolactone | S-(2'R,7R,8R,9S,10R,13S,14S)-10,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Human)	BDBM50228080 (Spiranolactone | S-(2'R,7R,8R,9S,10R,13S,14S)-10,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Human)	BDBM50228080 (Spiranolactone | S-(2'R,7R,8R,9S,10R,13S,14S)-10,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Human)	BDBM50228080 (Spiranolactone | S-(2'R,7R,8R,9S,10R,13S,14S)-10,1...) Show SMILES Show InChI	GoogleScholar	UniChem		2.32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Human)	BDBM50228080 (Spiranolactone | S-(2'R,7R,8R,9S,10R,13S,14S)-10,1...) Show SMILES Show InChI	GoogleScholar	UniChem		5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Human)	BDBM50228080 (Spiranolactone | S-(2'R,7R,8R,9S,10R,13S,14S)-10,1...) Show SMILES Show InChI	GoogleScholar	UniChem		32.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM50228080 (Spiranolactone | S-(2'R,7R,8R,9S,10R,13S,14S)-10,1...) Show SMILES Show InChI	GoogleScholar	UniChem		39.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Progesterone receptor (Human)	BDBM50228080 (Spiranolactone | S-(2'R,7R,8R,9S,10R,13S,14S)-10,1...) Show SMILES Show InChI	GoogleScholar	UniChem		400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor (Human)	BDBM50228080 (Spiranolactone | S-(2'R,7R,8R,9S,10R,13S,14S)-10,1...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair