BDBM50228755 ((S)-4-{[(S)-4-Guanidino-1-(thiazole-2-carbonyl)-butylcarbamoyl]-methyl}-3-oxo-1-phenylmethanesulfonyl-piperazin-2-yl)-acetic acid methyl ester::CHEMBL272961::methyl 2-((S)-1-(benzylsulfonyl)-4-(2-((S)-5-guanidino-1-oxo-1-(thiazol-2-yl)pentan-2-ylamino)-2-oxoethyl)-3-oxopiperazin-2-yl)acetate

SMILES [#6]-[#8]-[#6](=O)-[#6]-[#6@@H]-1-[#7](-[#6]-[#6]-[#7](-[#6]-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-c2nccs2)-[#6]-1=O)S(=O)(=O)[#6]-c1ccccc1

InChI Key InChIKey=OVBHVFLKMRIMFI-OALUTQOASA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50228755   

TargetProthrombin(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50228755(((S)-4-{[(S)-4-Guanidino-1-(thiazole-2-carbonyl)-b...)
Affinity DataIC50:  1.00E+3nMAssay Description:In vitro inhibitory activity against serine protease thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50228755(((S)-4-{[(S)-4-Guanidino-1-(thiazole-2-carbonyl)-b...)
Affinity DataIC50:  85nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50228755(((S)-4-{[(S)-4-Guanidino-1-(thiazole-2-carbonyl)-b...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human alpha-thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50228755(((S)-4-{[(S)-4-Guanidino-1-(thiazole-2-carbonyl)-b...)
Affinity DataIC50:  85nMAssay Description:In vitro inhibitory activity against factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed