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BDBM50229039 CHEMBL351568

SMILES: COC(=O)c1cccc(c1)-n1c2ccccc2c(=O)n(Cc2ccccc2)c1=O

InChI Key: InChIKey=XYCILAGNHIWZRO-UHFFFAOYSA-N

Data: 2 IC50

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50229039   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
cAMP-specific 3',5'-cyclic phosphodiesterase 4C


(Rattus norvegicus)
BDBM50229039
PNG
(CHEMBL351568)
Show SMILES COC(=O)c1cccc(c1)-n1c2ccccc2c(=O)n(Cc2ccccc2)c1=O
Show InChI InChI=1S/C23H18N2O4/c1-29-22(27)17-10-7-11-18(14-17)25-20-13-6-5-12-19(20)21(26)24(23(25)28)15-16-8-3-2-4-9-16/h2-14H,15H2,1H3
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 180n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]rolipram binding to Phosphodiesterase 4 in rat brain


J Med Chem 34: 624-8 (1991)


Article DOI: 10.1021/jm00106a024
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4C


(Rattus norvegicus)
BDBM50229039
PNG
(CHEMBL351568)
Show SMILES COC(=O)c1cccc(c1)-n1c2ccccc2c(=O)n(Cc2ccccc2)c1=O
Show InChI InChI=1S/C23H18N2O4/c1-29-22(27)17-10-7-11-18(14-17)25-20-13-6-5-12-19(20)21(26)24(23(25)28)15-16-8-3-2-4-9-16/h2-14H,15H2,1H3
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.00E+3n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of phosphodiesterase 4 from rat brain cortex


J Med Chem 34: 624-8 (1991)


Article DOI: 10.1021/jm00106a024
More data for this
Ligand-Target Pair