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BDBM50229176 CHEMBL161775

SMILES: [H][C@]12CCN(C[C@@]1([H])C[C@]1([H])N(CCc3ccccc13)C2)S(C)(=O)=O

InChI Key: InChIKey=MOXFACZZKFTOIR-INMHGKMJSA-N

Data: 2 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50229176   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Adrenergic receptor alpha-2


(RAT-NEONATAL RAT-Rattus norvegicus (rat))
BDBM50229176
PNG
(CHEMBL161775)
Show SMILES CS(=O)(=O)N1CC[C@@H]2CN3CCc4ccccc4[C@@H]3C[C@@H]2C1
Show InChI InChI=1S/C17H24N2O2S/c1-22(20,21)19-9-7-14-11-18-8-6-13-4-2-3-5-16(13)17(18)10-15(14)12-19/h2-5,14-15,17H,6-12H2,1H3/t14-,15-,17+/m1/s1
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
29n/an/an/an/an/an/an/an/a



Syntex Research

Curated by ChEMBL


Assay Description
Binding affinity to alpha-2 adrenergic receptor determined by measurement of [3H]yohimbine displacement from rat cortical membrane


J Med Chem 34: 705-17 (1991)


Article DOI: 10.1021/jm00106a036
More data for this
Ligand-Target Pair
Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor


(Rattus norvegicus (rat)-Rattus norvegicus (Rat))
BDBM50229176
PNG
(CHEMBL161775)
Show SMILES CS(=O)(=O)N1CC[C@@H]2CN3CCc4ccccc4[C@@H]3C[C@@H]2C1
Show InChI InChI=1S/C17H24N2O2S/c1-22(20,21)19-9-7-14-11-18-8-6-13-4-2-3-5-16(13)17(18)10-15(14)12-19/h2-5,14-15,17H,6-12H2,1H3/t14-,15-,17+/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
1.59E+3n/an/an/an/an/an/an/an/a



Syntex Research

Curated by ChEMBL


Assay Description
Binding affinity to alpha-1 adrenergic receptor determined by measurement of [3H]prazosin displacement from rat cortical membrane


J Med Chem 34: 705-17 (1991)


Article DOI: 10.1021/jm00106a036
More data for this
Ligand-Target Pair