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BDBM50229892 CHEMBL314406

SMILES: Cc1cc(N)c2cc(ccc2n1)C(=O)NCc1ccccc1

InChI Key: InChIKey=JCJTZFMGKDYEKW-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50229892   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
C5a anaphylatoxin chemotactic receptor


(Homo sapiens (Human))
BDBM50229892
PNG
(CHEMBL314406)
Show SMILES Cc1cc(N)c2cc(ccc2n1)C(=O)NCc1ccccc1
Show InChI InChI=1S/C18H17N3O/c1-12-9-16(19)15-10-14(7-8-17(15)21-12)18(22)20-11-13-5-3-2-4-6-13/h2-10H,11H2,1H3,(H2,19,21)(H,20,22)
PDB

KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a>100n/an/an/an/an/an/a



Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Ability to inhibit binding of radiolabeled C5a anaphylatoxin to intact membrane bound receptor from human neutrophils.


J Med Chem 35: 252-8 (1992)


Article DOI: 10.1021/jm00080a008
More data for this
Ligand-Target Pair