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BDBM50229893 CHEMBL315307

SMILES: Cc1ccc2cc(NC(=O)Nc3ccc4nc(C)ccc4c3)ccc2n1

InChI Key: InChIKey=CHWABNHLFWOHNX-UHFFFAOYSA-N

Data: 1 IC50

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50229893   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
C5a anaphylatoxin chemotactic receptor


(Homo sapiens (Human))
BDBM50229893
PNG
(CHEMBL315307)
Show SMILES Cc1ccc2cc(NC(=O)Nc3ccc4nc(C)ccc4c3)ccc2n1
Show InChI InChI=1S/C21H18N4O/c1-13-3-5-15-11-17(7-9-19(15)22-13)24-21(26)25-18-8-10-20-16(12-18)6-4-14(2)23-20/h3-12H,1-2H3,(H2,24,25,26)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a>50n/an/an/an/an/an/a


TBA

Assay Description
Ability to inhibit binding of radiolabeled C5a anaphylatoxin to intact membrane bound receptor from human neutrophils.


Citation and Details

Article DOI: 10.1021/jm00080a008
More data for this
Ligand-Target Pair