BDBM50231441 CHEMBL252031::N-(5-(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)ethyl)-2,3-dihydro-1H-inden-1-yl)propionamide

SMILES CCC(=O)NC1CCc2cc(CCN3CCN(CC3)c3nsc4ccccc34)ccc12

InChI Key InChIKey=BNPYZAAZLNWAPS-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50231441   

Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50231441(CHEMBL252031 | N-(5-(2-(4-(benzo[d]isothiazol-3-yl...)
Affinity DataKi:  0.25nMAssay Description:Displacement of [3H]ketanserin from human 5HT2A receptor expressed in Swiss 3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Rattus norvegicus (Rat))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50231441(CHEMBL252031 | N-(5-(2-(4-(benzo[d]isothiazol-3-yl...)
Affinity DataKi:  0.450nMAssay Description:Displacement of [3H]prazosin from rat adrenergic alpha1A receptor expressed in fibroblast cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50231441(CHEMBL252031 | N-(5-(2-(4-(benzo[d]isothiazol-3-yl...)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]8OHDPAT from human 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50231441(CHEMBL252031 | N-(5-(2-(4-(benzo[d]isothiazol-3-yl...)
Affinity DataKi:  184nMAssay Description:Displacement of [3H]dofetilide from human ERG channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed