BDBM50232232 4-(2-chlorophenyl)-8-(3-(dimethylamino)propoxy)-9-hydroxy-6-methylpyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione::4-(2-chlorophenyl)-8-[3-(dimethylamino)propoxy]-9-hydroxy-6-methylpyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione::CHEMBL410261

SMILES CN(C)CCCOc1cc2n(C)c3cc(c4C(=O)NC(=O)c4c3c2cc1O)-c1ccccc1Cl

InChI Key InChIKey=ZWRDUCSPTGMSHB-UHFFFAOYSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50232232   

TargetCyclin-dependent kinase 1(Homo sapiens (Human))
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM50232232(4-(2-chlorophenyl)-8-(3-(dimethylamino)propoxy)-9-...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human Cdc2 kinase PY15 phosphorylation in HT29 cells by Western blotMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetWee1-like protein kinase(Homo sapiens (Human))
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM50232232(4-(2-chlorophenyl)-8-(3-(dimethylamino)propoxy)-9-...)
Affinity DataIC50:  58nMAssay Description:Inhibition of human Wee1More data for this Ligand-Target Pair
TargetWee1-like protein kinase(Homo sapiens (Human))
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM50232232(4-(2-chlorophenyl)-8-(3-(dimethylamino)propoxy)-9-...)
Affinity DataIC50:  58nMAssay Description:Inhibition of human Wee1More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM50232232(4-(2-chlorophenyl)-8-(3-(dimethylamino)propoxy)-9-...)
Affinity DataIC50:  24nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed