BDBM50232822 CHEMBL4098409
SMILES Cl.COc1ccc2N(CCc2c1)c1nc(C)nc2c(Cc3ccccc3)c[nH]c12
InChI Key InChIKey=OECKCOWMOMORQW-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50232822
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: >200nMAssay Description:Inhibition of VEGFR-2 in human U251 cells assessed as reduction in VEGF induced phosphorylation preincubated for 60 mins followed by VEGF addition me...More data for this Ligand-Target Pair
Affinity DataIC50: 167nMAssay Description:Inhibition of EGFR in human A431 cells assessed as reduction in EGF induced phosphorylation preincubated for 60 mins followed by EGF addition measure...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: >200nMAssay Description:Inhibition of PDGFR-beta in human SF539 cells assessed as reduction in PDGF-BB induced phosphorylation preincubated for 60 mins followed by PDGF-BB a...More data for this Ligand-Target Pair