BDBM50233697 4-cyano-N-(4-(4-methylpiperazin-1-yl)-2-(piperidin-1-yl)phenyl)-1H-pyrrole-2-carboxamide::CHEMBL399763

SMILES CN1CCN(CC1)c1ccc(NC(=O)c2cc(c[nH]2)C#N)c(c1)N1CCCCC1

InChI Key InChIKey=NZRFILSWDBFAQV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50233697   

TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50233697(4-cyano-N-(4-(4-methylpiperazin-1-yl)-2-(piperidin...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of human cytoplasmic FMS expressed in Sf9-baculovirus system after 80 mins by fluorescence polarizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50233697(4-cyano-N-(4-(4-methylpiperazin-1-yl)-2-(piperidin...)
Affinity DataIC50:  2nMAssay Description:Inhibition of FMS mediated phosphorylation using SYEGNSYTFIDPTQ as substrate after 80 mins by fluorescence polarizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed