BDBM50233710 5-cyano-N-(4-(4-methylpiperazin-1-yl)-2-morpholinophenyl)furan-2-carboxamide::CHEMBL252832

SMILES CN1CCN(CC1)c1ccc(NC(=O)c2ccc(o2)C#N)c(c1)N1CCOCC1

InChI Key InChIKey=VTZUDEVOBJHTGP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50233710   

TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50233710(5-cyano-N-(4-(4-methylpiperazin-1-yl)-2-morpholino...)
Affinity DataIC50:  80nMAssay Description:Inhibition of human cytoplasmic FMS expressed in Sf9-baculovirus system after 80 mins by fluorescence polarizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed