BDBM50235800 Bambuterol::CHEBI:553827

SMILES CN(C)C(=O)Oc1cc(OC(=O)N(C)C)cc(c1)C(O)CNC(C)(C)C

InChI Key InChIKey=ANZXOIAKUNOVQU-UHFFFAOYSA-N

Data  12 IC50  2 Kon

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50235800   

TargetCholinesterase(Equus caballus (Horse))
South China University Of Technology

Curated by ChEMBL
LigandPNGBDBM50235800(Bambuterol | CHEBI:553827)
Affinity DataKoff:  2.40E+3s-1Assay Description:Antagonism of batrachotoxin-mediated sodium ion uptake into cultured neuroblastoma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
South China University Of Technology

Curated by ChEMBL
LigandPNGBDBM50235800(Bambuterol | CHEBI:553827)
Affinity DataKoff:  1.30E+5s-1Assay Description:Antagonism of batrachotoxin-mediated sodium ion uptake into cultured neuroblastoma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
South China University Of Technology

Curated by ChEMBL
LigandPNGBDBM50235800(Bambuterol | CHEBI:553827)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human erythrocytes AChE using S-acetylthiocholine iodide as substrate preincubated for 60 mins followed by substrate addition measured ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
South China University Of Technology

Curated by ChEMBL
LigandPNGBDBM50235800(Bambuterol | CHEBI:553827)
Affinity DataIC50:  119nMAssay Description:Inhibition of equine serum BuChE using S-butyrylthiocholine iodide as substrate preincubated for 60 mins followed by substrate addition measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
South China University Of Technology

Curated by ChEMBL
LigandPNGBDBM50235800(Bambuterol | CHEBI:553827)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of electric eel AChE using S-acetylthiocholine iodide as substrate preincubated for 60 mins followed by substrate addition measured after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
South China University Of Technology

Curated by ChEMBL
LigandPNGBDBM50235800(Bambuterol | CHEBI:553827)
Affinity DataIC50:  4.30nMAssay Description:Inhibition of human plasma BuChE using S-butyrylthiocholine iodide as substrate preincubated for 60 mins followed by substrate addition measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50235800(Bambuterol | CHEBI:553827)
Affinity DataIC50:  3nMAssay Description:Inhibition of rat BChEMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
South China University Of Technology

Curated by ChEMBL
LigandPNGBDBM50235800(Bambuterol | CHEBI:553827)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibitory concentration against cyclin dependent kinase-2 (CDK2)/Cyclin EMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
South China University Of Technology

Curated by ChEMBL
LigandPNGBDBM50235800(Bambuterol | CHEBI:553827)
Affinity DataIC50:  3nMAssay Description:Inhibition of BuChE (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
South China University Of Technology

Curated by ChEMBL
LigandPNGBDBM50235800(Bambuterol | CHEBI:553827)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
South China University Of Technology

Curated by ChEMBL
LigandPNGBDBM50235800(Bambuterol | CHEBI:553827)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCholinesterase(Homo sapiens (Human))
South China University Of Technology

Curated by ChEMBL
LigandPNGBDBM50235800(Bambuterol | CHEBI:553827)
Affinity DataIC50:  3nMAssay Description:Inhibition of BuchE (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50235800(Bambuterol | CHEBI:553827)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of rat AChEMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCholinesterase(Homo sapiens (Human))
South China University Of Technology

Curated by ChEMBL
LigandPNGBDBM50235800(Bambuterol | CHEBI:553827)
Affinity DataIC50:  3nMAssay Description:Inhibitory concentration against cyclin dependent kinase-2 (CDK2)/Cyclin EMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed