BDBM50236527 (-)-catechin::(2S,3R)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-chromene-3,5,7-triol::(2S,3R)-2-(3,4-dihydroxyphenyl)chroman-3,5,7-triol::(2S,3S)-2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxychroman-4-one::CHEMBL200715::Catechin

SMILES O[C@@H]1Cc2c(O)cc(O)cc2O[C@H]1c1ccc(O)c(O)c1

InChI Key InChIKey=PFTAWBLQPZVEMU-HIFRSBDPSA-N

Data  6 IC50  1 Kd

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50236527   

TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
University Of Pennsylvania School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50236527((-)-catechin | (2S,3R)-2-(3,4-dihydroxyphenyl)-3,4...)
Affinity DataIC50:  5.30E+3nMAssay Description:Inhibition of peroxidase activity of COX1 in heep seminal vesicle by TMPD assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
University Of Pennsylvania School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50236527((-)-catechin | (2S,3R)-2-(3,4-dihydroxyphenyl)-3,4...)
Affinity DataIC50:  3.08E+4nMAssay Description:Inhibition of cyclooxygenase activity of COX1 in sheep seminal vesicle in presence of 1 mM phenol by cyclooxygenase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSialidase-2(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50236527((-)-catechin | (2S,3R)-2-(3,4-dihydroxyphenyl)-3,4...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human Neu2 assessed as MuNANA substrate hydrolysis in presence of 0.1% Triton X-100 by discontinuous fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable maltase-glucoamylase 2(Homo sapiens)
Volgograd State Medical University

Curated by ChEMBL
LigandPNGBDBM50236527((-)-catechin | (2S,3R)-2-(3,4-dihydroxyphenyl)-3,4...)
Affinity DataIC50:  5.38E+4nMAssay Description:Inhibition of alpha-glucosidase (unknown origin) using p-nitrophenyl beta-D-glucopyranoside as substrate measured after 20 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target6-phosphogluconate dehydrogenase, decarboxylating(Homo sapiens (Human))
Amorepacific

Curated by ChEMBL
LigandPNGBDBM50236527((-)-catechin | (2S,3R)-2-(3,4-dihydroxyphenyl)-3,4...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of 6PGDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
University Of Pennsylvania School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50236527((-)-catechin | (2S,3R)-2-(3,4-dihydroxyphenyl)-3,4...)
Affinity DataKd:  4.87E+4nMAssay Description:Binding affinity to COX1 in sheep seminal vesicleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-6-phosphate 1-dehydrogenase(Saccharomyces cerevisiae S288c)
Amorepacific

Curated by ChEMBL
LigandPNGBDBM50236527((-)-catechin | (2S,3R)-2-(3,4-dihydroxyphenyl)-3,4...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of yeast G6PDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed