BDBM50236856 CHEMBL272198::N-cyclopropyl-6-(6,7-dimethoxyquinolin-4-yloxy)-1-naphthamide::N-cyclopropyl-6-[(6,7-dimethoxyquinolin-4-yl)oxy]naphthalene-1-carboxamide

SMILES: COc1cc2c(ccnc2cc1OC)Oc3ccc4c(c3)cccc4C(=O)NC5CC5

InChI Key: InChIKey=ZATGFXTWDKIEKC-UHFFFAOYSA-N

Data: 12 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50236856   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aurora kinase B (Human)	BDBM50236856 (N-cyclopropyl-6-[(6,7-dimethoxyquinolin-4-yl)oxy]n...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	118	n/a	n/a	n/a	n/a	n/a	n/a
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Angiopoietin-1 receptor (Human)	BDBM50236856 (N-cyclopropyl-6-[(6,7-dimethoxyquinolin-4-yl)oxy]n...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Hepatocyte growth factor receptor (Human)	BDBM50236856 (N-cyclopropyl-6-[(6,7-dimethoxyquinolin-4-yl)oxy]n...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Lck (Human)	BDBM50236856 (N-cyclopropyl-6-[(6,7-dimethoxyquinolin-4-yl)oxy]n...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
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Aurora kinase A (Human)	BDBM50236856 (N-cyclopropyl-6-[(6,7-dimethoxyquinolin-4-yl)oxy]n...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase ABL1 (Human)	BDBM50236856 (N-cyclopropyl-6-[(6,7-dimethoxyquinolin-4-yl)oxy]n...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	466	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Fgr (Human)	BDBM50236856 (N-cyclopropyl-6-[(6,7-dimethoxyquinolin-4-yl)oxy]n...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	396	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Lyn (Human)	BDBM50236856 (N-cyclopropyl-6-[(6,7-dimethoxyquinolin-4-yl)oxy]n...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 2 (Human)	BDBM50236856 (N-cyclopropyl-6-[(6,7-dimethoxyquinolin-4-yl)oxy]n...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 2 (Human)	BDBM50236856 (N-cyclopropyl-6-[(6,7-dimethoxyquinolin-4-yl)oxy]n...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 2 (Human)	BDBM50236856 (N-cyclopropyl-6-[(6,7-dimethoxyquinolin-4-yl)oxy]n...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 2 (Human)	BDBM50236856 (N-cyclopropyl-6-[(6,7-dimethoxyquinolin-4-yl)oxy]n...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.603	n/a	n/a	n/a	n/a	n/a	n/a
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