BDBM50238827 CHEMBL4064328

SMILES Fc1ccc2[nH]c(nc2c1)[C@@H]1CCN(CC2NC=CN2)C1

InChI Key InChIKey=FRIWTGPMPWVNBD-SNVBAGLBSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50238827   

TargetLactoperoxidase(Bos taurus (Bovine))
Universit£

Curated by ChEMBL
LigandPNGBDBM50238827(CHEMBL4064328)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of bovine milk LPO assessed as reduction in NaOSCN production in presence of H2O2/NaSCN after 5 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMyeloperoxidase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50238827(CHEMBL4064328)
Affinity DataIC50:  50nMAssay Description:Inhibition of recombinant MPO (unknown origin) assessed as reduction in taurine chloramine production preincubated with enzyme and taurine followed b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMyeloperoxidase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50238827(CHEMBL4064328)
Affinity DataIC50:  120nMAssay Description:Inhibition of recombinant MPO (unknown origin) assessed as reduction in LDL oxidation in presence of H2O2 and HCl after 5 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMyeloperoxidase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50238827(CHEMBL4064328)
Affinity DataIC50:  3.14E+5nMAssay Description:Inhibition of MPO in human neutrophils assessed as reduction in HOCl production preincubated for 30 mins followed by H2O2 addition by APF staining ba...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed