BDBM50239833 (3-bromo-7-cyanonaphthalen-2-yl)difluoromethylphosphonic acid::CHEMBL259628::US10150787, Example 10::US11597739, Example 10::[(3-bromo-7-cyano-2-naphthyl)-(difluoro)methyl]phosphonic acid
SMILES OP(O)(=O)C(F)(F)c1cc2cc(ccc2cc1Br)C#N
InChI Key InChIKey=BWJOQFMMTKEZGA-UHFFFAOYSA-N
Data 7 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50239833
Affinity DataIC50: 490nMAssay Description:Activity of the compounds of this application may be evaluated using the following assays for TC-PTP-inhibiting activity. Compounds of Formula I will...More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CD45 by fluorescein diphosphate assayMore data for this Ligand-Target Pair
Affinity DataIC50: 490nMAssay Description:The assay was carried out at room temperature in 96 well plates. The reaction mixture in 170 μl contained 50 mM Bis-Tris (pH=6.3), 2 mM EDTA, 5 ...More data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Inhibition of PTP1B by fluorescein diphosphate assayMore data for this Ligand-Target Pair