BDBM50241050 2-(6-fluoro-1H-indol-3-yl)ethanamine::6-fluorotryptamine::CHEMBL381160

SMILES NCCc1c[nH]c2cc(F)ccc12

InChI Key InChIKey=BQTOKMYKZPCPRW-UHFFFAOYSA-N

Data  1 Kd  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50241050   

TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50241050(2-(6-fluoro-1H-indol-3-yl)ethanamine | 6-fluorotry...)
Affinity DataEC50:  4.40nMAssay Description:Induction of 5-HTT-mediated 5-HT release in rat brain synaptosomes by [3H]5-HT release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50241050(2-(6-fluoro-1H-indol-3-yl)ethanamine | 6-fluorotry...)
Affinity DataEC50:  1.58E+3nMAssay Description:Induction of NET-mediated norepinephrine release in rat brain synaptosomes by [3H]NE release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Institut FüR Biochemie

Curated by ChEMBL
LigandPNGBDBM50241050(2-(6-fluoro-1H-indol-3-yl)ethanamine | 6-fluorotry...)
Affinity DataKd:  6.90E+6nMAssay Description:Binding affinity to thrombin (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50241050(2-(6-fluoro-1H-indol-3-yl)ethanamine | 6-fluorotry...)
Affinity DataEC50:  4.60nMAssay Description:Agonist activity at 5HT2A receptor (unknown origin) by cell based calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50241050(2-(6-fluoro-1H-indol-3-yl)ethanamine | 6-fluorotry...)
Affinity DataEC50:  106nMAssay Description:Induction of DAT-mediated dopamine release in rat brain synaptosomes by [3H]DA release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed