BDBM50243880 3-(3,4,5-Trimethoxyphenyl)-4-(1-{[2-(trimethylsilyl)ethoxy]-methyl}-1H-indol-3-yl)-1,5-dihydro-2H-pyrrole-2-one::CHEMBL486437

SMILES: COc1cc(cc(OC)c1OC)C1=C(CNC1=O)c1cn(COCC[Si](C)(C)C)c2ccccc12

InChI Key: InChIKey=OBFNFWMFLWGMPB-UHFFFAOYSA-N

Data: 8 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50243880   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 3 (Human)	BDBM50243880 (3-(3,4,5-Trimethoxyphenyl)-4-(1-{[2-(trimethylsily...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM50243880 (3-(3,4,5-Trimethoxyphenyl)-4-(1-{[2-(trimethylsily...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Ephrin type-B receptor 4 (Human)	BDBM50243880 (3-(3,4,5-Trimethoxyphenyl)-4-(1-{[2-(trimethylsily...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Insulin-like growth factor 1 receptor (Human)	BDBM50243880 (3-(3,4,5-Trimethoxyphenyl)-4-(1-{[2-(trimethylsily...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM50243880 (3-(3,4,5-Trimethoxyphenyl)-4-(1-{[2-(trimethylsily...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 2 (Human)	BDBM50243880 (3-(3,4,5-Trimethoxyphenyl)-4-(1-{[2-(trimethylsily...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Receptor-type tyrosine-protein kinase FLT3 (Human)	BDBM50243880 (3-(3,4,5-Trimethoxyphenyl)-4-(1-{[2-(trimethylsily...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Angiopoietin-1 receptor (Human)	BDBM50243880 (3-(3,4,5-Trimethoxyphenyl)-4-(1-{[2-(trimethylsily...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
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