BDBM50243931 4-[1-(Phenoxymethyl)-1H-indol-3-yl]-3-(3,4,5-trimethoxyphenyl)-1,5-dihydro-2H-pyrrole-2-one::CHEMBL488811

SMILES: COc1cc(cc(OC)c1OC)C1=C(CNC1=O)c1cn(COc2ccccc2)c2ccccc12

InChI Key: InChIKey=GCWMGQFAGIVZCJ-UHFFFAOYSA-N

Data: 14 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50243931   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 3 (Human)	BDBM50243931 (4-[1-(Phenoxymethyl)-1H-indol-3-yl]-3-(3,4,5-trime...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Insulin receptor (Human)	BDBM50243931 (4-[1-(Phenoxymethyl)-1H-indol-3-yl]-3-(3,4,5-trime...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Aurora kinase B (Human)	BDBM50243931 (4-[1-(Phenoxymethyl)-1H-indol-3-yl]-3-(3,4,5-trime...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Aurora kinase A (Human)	BDBM50243931 (4-[1-(Phenoxymethyl)-1H-indol-3-yl]-3-(3,4,5-trime...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 2 (Human)	BDBM50243931 (4-[1-(Phenoxymethyl)-1H-indol-3-yl]-3-(3,4,5-trime...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 4 (Human)	BDBM50243931 (4-[1-(Phenoxymethyl)-1H-indol-3-yl]-3-(3,4,5-trime...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Receptor tyrosine-protein kinase erbB-2 (Human)	BDBM50243931 (4-[1-(Phenoxymethyl)-1H-indol-3-yl]-3-(3,4,5-trime...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Focal adhesion kinase 1 (Human)	BDBM50243931 (4-[1-(Phenoxymethyl)-1H-indol-3-yl]-3-(3,4,5-trime...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM50243931 (4-[1-(Phenoxymethyl)-1H-indol-3-yl]-3-(3,4,5-trime...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 2 (Human)	BDBM50243931 (4-[1-(Phenoxymethyl)-1H-indol-3-yl]-3-(3,4,5-trime...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Angiopoietin-1 receptor (Human)	BDBM50243931 (4-[1-(Phenoxymethyl)-1H-indol-3-yl]-3-(3,4,5-trime...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase kinase kinase 8 (Human)	BDBM50243931 (4-[1-(Phenoxymethyl)-1H-indol-3-yl]-3-(3,4,5-trime...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Hepatocyte growth factor receptor (Human)	BDBM50243931 (4-[1-(Phenoxymethyl)-1H-indol-3-yl]-3-(3,4,5-trime...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase PLK4 (Human)	BDBM50243931 (4-[1-(Phenoxymethyl)-1H-indol-3-yl]-3-(3,4,5-trime...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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