BDBM50245855 CHEMBL450918::N3-(2,6-dimethylphenyl)-N6-(3-fluoro-4-(3-(piperidin-1-yl)propoxy)phenyl)-1-(3-methoxy-3-methylbutyl)-1H-pyrazolo[3,4-d]pyrimidine-3,6-diamine

SMILES COC(C)(C)CCn1nc(Nc2c(C)cccc2C)c2cnc(Nc3ccc(OCCCN4CCCCC4)c(F)c3)nc12

InChI Key InChIKey=YBYFISXTSWTCCW-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50245855   

TargetActivated CDC42 kinase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50245855(CHEMBL450918 | N3-(2,6-dimethylphenyl)-N6-(3-fluor...)
Affinity DataKi:  3nMAssay Description:Inhibition of histidine-tagged ACK1 (amino acids 117 to 489) (unknown origin) expressed in SF9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50245855(CHEMBL450918 | N3-(2,6-dimethylphenyl)-N6-(3-fluor...)
Affinity DataKi:  60nMAssay Description:Inhibition of flag-tagged ACK1 (unknown origin) autophosphorylation expressed in human 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed