BDBM50246894 CHEMBL4087657

SMILES COc1cc(Oc2ccc(NS(=O)(=O)c3ccc(NC(C)=O)cc3)cc2C#N)ccc1Cl

InChI Key InChIKey=KACIKJVEXIWMLU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50246894   

TargetPlatelet-activating factor acetylhydrolase(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50246894(CHEMBL4087657)
Affinity DataIC50: 924nMAssay Description:Inhibition of human recombinant GST-tagged Lp-PLA2 (47 to 429 residues) expressed in Escherichia coli Rosetta(DE3) pLysS using 2-thio-PAF as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details Article
PubMed