BDBM50247490 4-amino-3-(4-(hexyloxy)phenyl)-4-oxobutanoic acid::CHEMBL448246::cid_651854

SMILES CCCCCCOc1ccc(cc1)C(CC(O)=O)C(N)=O

InChI Key InChIKey=RRXQHLQCQYPPMF-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50247490   

TargetMatrix metalloproteinase-9(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50247490(cid_651854 | CHEMBL448246 | 4-amino-3-(4-(hexyloxy...)
Affinity DataIC50: 160nMAssay Description:Inhibition of human recombinant MMP9 by fluorogenic substrate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50247490(cid_651854 | CHEMBL448246 | 4-amino-3-(4-(hexyloxy...)
Affinity DataIC50: 670nMAssay Description:Inhibition of human recombinant MMP8 by fluorogenic substrate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50247490(cid_651854 | CHEMBL448246 | 4-amino-3-(4-(hexyloxy...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human recombinant MMP13 by fluorogenic substrate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50247490(cid_651854 | CHEMBL448246 | 4-amino-3-(4-(hexyloxy...)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of human recombinant MMP13 expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50247490(cid_651854 | CHEMBL448246 | 4-amino-3-(4-(hexyloxy...)
Affinity DataIC50: 4.82E+3nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2011
Entry Details
PCBioAssay
TargetCollagenase 3(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50247490(cid_651854 | CHEMBL448246 | 4-amino-3-(4-(hexyloxy...)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of human recombinant MMP13 by HxBPyne probe-based competitive activity based protein profiling assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed