BDBM50248235 CHEBI:5136::CHEMBL350239

SMILES CC(C)n1c(\C=C\[C@H](O)C[C@H](O)CC(O)=O)c(-c2ccc(F)cc2)c2ccccc12

InChI Key InChIKey=FJLGEFLZQAZZCD-JUFISIKESA-N

Data  3 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50248235   

TargetATP-binding cassette sub-family C member 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50248235(CHEBI:5136 | CHEMBL350239)
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile salt export pump(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50248235(CHEBI:5136 | CHEMBL350239)
Affinity DataIC50:  3.61E+4nMAssay Description:Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacylase sirtuin-6(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50248235(CHEBI:5136 | CHEMBL350239)
Affinity DataEC50:  7.10E+3nMAssay Description:Antagonist activity at adrenergic alpha1A receptor in rat tail arteryMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNAD-dependent protein deacylase sirtuin-6(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50248235(CHEBI:5136 | CHEMBL350239)
Affinity DataEC50:  7.10E+3nMAssay Description:Antagonist activity at adrenergic alpha1A receptor in rat tail arteryMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetATP-binding cassette sub-family C member 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50248235(CHEBI:5136 | CHEMBL350239)
Affinity DataIC50:  5.70E+4nMAssay Description:Inhibition of human MRP3 overexpressed in Sf9 insect cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed