BDBM50248522 CHEMBL489332::N-hydroxy-3-(2-phenethyl-1-(2-(piperidin-1-yl)ethyl)-1H-benzo[d]imidazol-5-yl)acrylamide::US10201527, Compound 67::US10736881, Compound 67::US8551988, 67

SMILES: ONC(=O)\C=C\c1ccc2n(CCN3CCCCC3)c(CCc3ccccc3)nc2c1

InChI Key: InChIKey=XZWCFUZJOAZGAI-UHFFFAOYSA-N

Data: 9 KI  8 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 18 hits for monomerid = 50248522   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 8 (Human)	BDBM50248522 (CHEMBL489332 | US8551988, 67 | N-hydroxy-3-(2-phen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	254	n/a	n/a	n/a	n/a	n/a	n/a
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Histone H3.1 (Human)	BDBM50248522 (CHEMBL489332 | US8551988, 67 | N-hydroxy-3-(2-phen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	500	n/a	n/a	n/a	n/a
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Histone deacetylase 1 (Human)	BDBM50248522 (CHEMBL489332 | US8551988, 67 | N-hydroxy-3-(2-phen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
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Histone deacetylase 8 (Human)	BDBM50248522 (CHEMBL489332 | US8551988, 67 | N-hydroxy-3-(2-phen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	254	n/a	n/a	n/a	n/a	n/a	n/a
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Histone deacetylase 1 (Human)	BDBM50248522 (CHEMBL489332 | US8551988, 67 | N-hydroxy-3-(2-phen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
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Histone deacetylase 8 (Human)	BDBM50248522 (CHEMBL489332 | US8551988, 67 | N-hydroxy-3-(2-phen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	254	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Histone deacetylase 1 (Human)	BDBM50248522 (CHEMBL489332 | US8551988, 67 | N-hydroxy-3-(2-phen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Histone deacetylase 1 (Human)	BDBM50248522 (CHEMBL489332 | US8551988, 67 | N-hydroxy-3-(2-phen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Histone deacetylase 1 (Human)	BDBM50248522 (CHEMBL489332 | US8551988, 67 | N-hydroxy-3-(2-phen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
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Histone deacetylase 4 (Human)	BDBM50248522 (CHEMBL489332 | US8551988, 67 | N-hydroxy-3-(2-phen...) Show SMILES Show InChI	GoogleScholar	UniChem		8.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Histone deacetylase 3 (Human)	BDBM50248522 (CHEMBL489332 | US8551988, 67 | N-hydroxy-3-(2-phen...) Show SMILES Show InChI	GoogleScholar	UniChem		11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Histone deacetylase 1 (Human)	BDBM50248522 (CHEMBL489332 | US8551988, 67 | N-hydroxy-3-(2-phen...) Show SMILES Show InChI	GoogleScholar	UniChem		12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Histone deacetylase 11 (Human)	BDBM50248522 (CHEMBL489332 | US8551988, 67 | N-hydroxy-3-(2-phen...) Show SMILES Show InChI	GoogleScholar	UniChem		14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Histone deacetylase 5 (Human)	BDBM50248522 (CHEMBL489332 | US8551988, 67 | N-hydroxy-3-(2-phen...) Show SMILES Show InChI	GoogleScholar	UniChem		18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Polyamine deacetylase HDAC10 (Human)	BDBM50248522 (CHEMBL489332 | US8551988, 67 | N-hydroxy-3-(2-phen...) Show SMILES Show InChI	GoogleScholar	UniChem		23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Histone deacetylase 9 (Human)	BDBM50248522 (CHEMBL489332 | US8551988, 67 | N-hydroxy-3-(2-phen...) Show SMILES Show InChI	GoogleScholar	UniChem		24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Histone deacetylase 6 (Human)	BDBM50248522 (CHEMBL489332 | US8551988, 67 | N-hydroxy-3-(2-phen...) Show SMILES Show InChI	GoogleScholar	UniChem		27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Histone deacetylase 2 (Human)	BDBM50248522 (CHEMBL489332 | US8551988, 67 | N-hydroxy-3-(2-phen...) Show SMILES Show InChI	GoogleScholar	UniChem		39	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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