BDBM50250266 CHEMBL1603838

SMILES O=C(NC1CCN(Cc2ccccc2)CC1)c1ccccc1

InChI Key InChIKey=LDGORKJXEGHFBK-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50250266   

TargetSodium- and chloride-dependent betaine transporter(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50250266(CHEMBL1603838)
Affinity DataIC50: 2.90E+5nMAssay Description:Inhibition of human BGT1 expresses in tsA201 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2019
Entry Details Article
PubMed
TargetSodium- and chloride-dependent betaine transporter(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50250266(CHEMBL1603838)
Affinity DataIC50: 2.95E+5nMAssay Description:Inhibition of human BGT1 expresses in tsA201 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2019
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50250266(CHEMBL1603838)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human GAT2 expresses in tsA201 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2019
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50250266(CHEMBL1603838)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human GAT1 expresses in tsA201 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2019
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 3(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50250266(CHEMBL1603838)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human GAT3 expresses in tsA201 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2019
Entry Details Article
PubMed