BDBM50251887 3-(3-((2-cyano-7-(2-cyclohexylethyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl)methoxy)phenyl)propanoic acid::CHEMBL482268

SMILES OC(=O)CCc1cccc(OCc2cc3cnc(nc3n2CCC2CCCCC2)C#N)c1

InChI Key InChIKey=UHQGMIAMZZAVQJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50251887   

TargetCathepsin S(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50251887(3-(3-((2-cyano-7-(2-cyclohexylethyl)-7H-pyrrolo[2,...)
Affinity DataIC50: 6nMAssay Description:Inhibition of human recombinant cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50251887(3-(3-((2-cyano-7-(2-cyclohexylethyl)-7H-pyrrolo[2,...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human recombinant cathepsin L by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCathepsin K(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50251887(3-(3-((2-cyano-7-(2-cyclohexylethyl)-7H-pyrrolo[2,...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human recombinant cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed