BDBM50252978 (2'Z-3'E)-6-Bromoindirubin-3'-[O-(2-pyrrolidin-1-ylethyl)oxime]::CHEMBL493883::CHEMBL494685

SMILES: Brc1ccc2\C(C(=O)Nc2c1)=C1\Nc2ccccc2\C\1=N/OCCN1CCCC1

InChI Key: InChIKey=KNGAOBKKLCKYNZ-UHFFFAOYSA-N

Data: 12 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50252978   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK2 (Human)	BDBM50252978 (CHEMBL493883 | CHEMBL494685 | (2'Z-3'E)-6-Bromoind...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.41E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM50252978 (CHEMBL493883 | CHEMBL494685 | (2'Z-3'E)-6-Bromoind...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase ABL1 (Human)	BDBM50252978 (CHEMBL493883 | CHEMBL494685 | (2'Z-3'E)-6-Bromoind...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	67	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase ABL1 (Human)	BDBM50252978 (CHEMBL493883 | CHEMBL494685 | (2'Z-3'E)-6-Bromoind...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.94E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Aurora kinase A (Human)	BDBM50252978 (CHEMBL493883 | CHEMBL494685 | (2'Z-3'E)-6-Bromoind...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	175	n/a	n/a	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM50252978 (CHEMBL493883 | CHEMBL494685 | (2'Z-3'E)-6-Bromoind...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.90	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase JAK2 (Human)	BDBM50252978 (CHEMBL493883 | CHEMBL494685 | (2'Z-3'E)-6-Bromoind...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.46E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Human)	BDBM50252978 (CHEMBL493883 | CHEMBL494685 | (2'Z-3'E)-6-Bromoind...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.56E+3	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Aurora kinase A (Human)	BDBM50252978 (CHEMBL493883 | CHEMBL494685 | (2'Z-3'E)-6-Bromoind...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	79	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Human)	BDBM50252978 (CHEMBL493883 | CHEMBL494685 | (2'Z-3'E)-6-Bromoind...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	107	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 1 (Human)	BDBM50252978 (CHEMBL493883 | CHEMBL494685 | (2'Z-3'E)-6-Bromoind...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	450	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Human)	BDBM50252978 (CHEMBL493883 | CHEMBL494685 | (2'Z-3'E)-6-Bromoind...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair